/* =========================================================
   RESET + BASE
========================================================= */
*,
*::before,
*::after { box-sizing: border-box; }

html, body {
  margin: 0;
  padding: 0;
  min-height: 100%;
  background-color: #eaf6fd;
  overscroll-behavior: none;
}

/* =========================================================
   VARIABLES (PREMIUM CLÍNICO)
========================================================= */
:root{
  --bg: #eaf6fd;
  --bg-soft: #f6fbff;
  --panel: rgba(255,255,255,.72);
  --panel-solid: #ffffff;

  --card: #d8eefb;
  --border: #b9dced;
  --border-soft: rgba(185,220,237,.65);

  --text: #0f172a;
  --muted: #475569;

  --accent: #38bdf8;
  --accent-strong: #0284c7;
  --accent-soft: rgba(56,189,248,.18);

  --shadow-sm: 0 6px 18px rgba(2,132,199,.08);
  --shadow: 0 14px 40px rgba(2,132,199,.12);
  --shadow-hover: 0 18px 52px rgba(2,132,199,.18);

  --radius: 20px;
  --radius-md: 14px;
}

/* =========================================================
   APP ROOT
========================================================= */
.app-root{
  min-height: 100dvh;
  display: flex;
  flex-direction: column;

  background:
    radial-gradient(900px 450px at 10% -10%, rgba(56,189,248,.22), transparent 60%),
    radial-gradient(700px 350px at 90% 10%, rgba(2,132,199,.16), transparent 55%),
    linear-gradient(180deg, rgba(255,255,255,.65), rgba(255,255,255,0)),
    var(--bg);

  color: var(--text);
  font-family: system-ui, -apple-system, Segoe UI, Roboto, Arial, sans-serif;
  line-height: 1.55;
  -webkit-font-smoothing: antialiased;
  text-rendering: optimizeLegibility;
}

/* =========================================================
   LAYOUT
========================================================= */
.container{
  flex: 1;
  width: min(1100px, 100%);
  margin: 0 auto;
  padding: 2.25rem 1.25rem 4rem;
}

/* =========================================================
   TIPOGRAFÍA
========================================================= */
h1,h2,h3,h4{
  margin: 0;
  letter-spacing: -0.02em;
}

h2{
  margin: 2.2rem 0 1rem;
  font-size: 1.28rem;
}

.muted{ color: var(--muted); }

/* =========================================================
   LINKS
========================================================= */
a{
  color: var(--accent-strong);
  text-decoration: none;
  transition: color .2s ease, opacity .2s ease;
}
a:hover{ color: var(--accent); }

/* =========================================================
   LANGUAGE SWITCHER (PRO)
========================================================= */
.language-switcher{
  text-align: right;
  font-size: 0.85rem;
  margin-bottom: 1rem;
  color: var(--muted);
}

.language-switcher a{
  color: var(--muted);
  text-decoration: none;
  margin-left: 0.4rem;
  font-weight: 650;
}
.language-switcher a:hover{ color: var(--accent-strong); }
.language-switcher .active{ color: var(--text); font-weight: 800; }

/* =========================================================
   BREADCRUMB (SI LO USÁS EN ESTA PÁGINA)
========================================================= */
.breadcrumb{
  display: inline-flex;
  align-items: center;
  gap: .45rem;
  padding: .55rem .8rem;
  border: 1px solid var(--border-soft);
  border-radius: 999px;
  background: rgba(255,255,255,.55);
  backdrop-filter: blur(10px);
  box-shadow: var(--shadow-sm);
  font-size: .84rem;
  color: var(--muted);
  margin: 0 0 1.25rem;
}

.breadcrumb a{ font-weight: 700; }
.breadcrumb span{ opacity: .55; }

/* =========================================================
   CARD / PANEL
========================================================= */
.card{
  background: linear-gradient(180deg, rgba(255,255,255,.78), rgba(255,255,255,.62));
  border: 1px solid var(--border-soft);
  border-radius: var(--radius);
  padding: 1.55rem;
  box-shadow: var(--shadow);
  backdrop-filter: blur(10px);
}

/* =========================================================
   CONTROLES
========================================================= */
.controls{ margin-bottom: 1.5rem; }

.controls-grid{
  display: grid;
  gap: 1rem;
  align-items: end;
}

@media (min-width: 860px){
  .controls-grid{ grid-template-columns: 2fr 1fr auto; }
}

label{
  display: block;
  font-size: 0.8rem;
  color: var(--muted);
  margin-bottom: 0.35rem;
  font-weight: 650;
}

/* =========================================================
   INPUTS / SELECTS (PREMIUM)
========================================================= */
input[type="search"],
input[type="number"],
select{
  width: 100%;
  padding: 0.75rem 0.85rem;
  border-radius: 12px;
  border: 1px solid var(--border);
  background: var(--panel-solid);
  color: var(--text);
  outline: none;
  transition: border-color .15s ease, box-shadow .15s ease, transform .15s ease;
}

input::placeholder{ color: rgba(71,85,105,.7); }

input:focus,
select:focus{
  border-color: var(--accent);
  box-shadow: 0 0 0 3px var(--accent-soft);
}

input:focus-visible,
select:focus-visible,
button:focus-visible,
a:focus-visible{
  outline: 3px solid rgba(56,189,248,.45);
  outline-offset: 2px;
  border-radius: 12px;
}

/* =========================================================
   BOTONES (PRODUCT)
========================================================= */
.btn{
  border: 1px solid transparent;
  border-radius: 14px;
  padding: 0.78rem 1.08rem;
  font-weight: 800;
  cursor: pointer;
  transition: transform .15s ease, box-shadow .15s ease, background .15s ease, border-color .15s ease;
  white-space: nowrap;
}

.btn:active{ transform: translateY(1px); }

.btn.secondary{
  background: rgba(255,255,255,.85);
  color: var(--accent-strong);
  border-color: rgba(56,189,248,.55);
}

.btn.secondary:hover{
  background: rgba(56,189,248,.10);
  box-shadow: 0 10px 22px rgba(2,132,199,.12);
  transform: translateY(-1px);
}

.btn.toggle-sheet{
  background: linear-gradient(180deg, var(--accent), var(--accent-strong));
  color: #001018;
  border-color: rgba(2,132,199,.25);
  box-shadow: 0 10px 22px rgba(2,132,199,.18);
}

.btn.toggle-sheet:hover{
  transform: translateY(-2px);
  box-shadow: 0 14px 30px rgba(2,132,199,.26);
}

/* =========================================================
   DRUG CARD (MÁS PRO)
========================================================= */
.drug-card{
  background: rgba(255,255,255,.9);
  border: 1px solid var(--border-soft);
  border-radius: var(--radius);
  padding: 1.15rem 1.2rem;
  margin-bottom: 1rem;
  box-shadow: var(--shadow-sm);
  transition: transform .15s ease, border-color .15s ease, box-shadow .15s ease, background .15s ease;
}

.drug-card:hover{
  transform: translateY(-3px);
  border-color: rgba(56,189,248,.65);
  box-shadow: var(--shadow-hover);
  background: rgba(255,255,255,.96);
}

.drug-head{
  display: flex;
  justify-content: space-between;
  align-items: center;
  gap: 1rem;
}

.drug-head strong{
  font-size: 1.02rem;
  letter-spacing: -0.01em;
}

/* =========================================================
   FICHA CLÍNICA
========================================================= */
.hidden{ display: none !important; }

.drug-sheet{
  margin-top: 1rem;
  padding-top: 1rem;
  border-top: 1px solid var(--border-soft);
  display: grid;
  gap: 0.85rem;
}

/* =========================================================
   BLOQUE CÁLCULO
========================================================= */
.calc-grid{
  display: grid;
  gap: 0.85rem;
}

@media (min-width: 860px){
  .calc-grid{ grid-template-columns: repeat(3, 1fr); }
}

.calc-result{
  padding: .85rem 1rem;
  border-radius: 14px;
  border: 1px solid var(--border-soft);
  background: rgba(234,246,253,.65);
}

.calc-result span{
  display: block;
  font-size: 0.75rem;
  color: var(--muted);
  font-weight: 650;
}

.calc-result b{
  font-size: 1.02rem;
  color: var(--text);
}

/* =========================================================
   NOTA CLÍNICA
========================================================= */
.clinical-note{
  margin-top: 1rem;
  padding: 0.95rem 1.05rem;
  border-radius: 16px;
  background: rgba(56,189,248,.10);
  border: 1px dashed rgba(56,189,248,.40);
  color: var(--text);
  font-size: 0.92rem;
}

/* =========================================================
   SECCIONES H2
========================================================= */
main h2{
  margin: 3rem 0 1.25rem;
  padding-top: 1.25rem;
  border-top: 1px solid var(--border-soft);
}

main h2:first-of-type{
  margin-top: 2rem;
  padding-top: 0;
  border-top: none;
}

main h2::before{
  content: "";
  display: block;
  width: 52px;
  height: 3px;
  background: linear-gradient(90deg, var(--accent), var(--accent-strong));
  border-radius: 2px;
  margin-bottom: 0.65rem;
}

/* =========================================================
   FOOTER (CENTRADO + INSTITUCIONAL)
========================================================= */
footer{
  text-align: center;
  padding: 2.2rem 1.25rem;
  border-top: 1px solid var(--border-soft);
  color: var(--muted);
  background: rgba(255,255,255,.55);
  backdrop-filter: blur(10px);
}

.footer-nav{
  display: inline-flex;
  justify-content: center;
  align-items: center;
  gap: 0.6rem;
  flex-wrap: wrap;
  margin-bottom: 0.85rem;
  padding: .55rem .85rem;
  border: 1px solid var(--border-soft);
  border-radius: 999px;
  background: rgba(255,255,255,.65);
}

.footer-nav a{
  color: var(--accent-strong);
  font-weight: 800;
}

.footer-nav a:hover{ color: var(--accent); }

footer p{
  max-width: 760px;
  margin: 0 auto;
  font-size: .82rem;
  line-height: 1.5;
}

/* =========================================================
   RESPONSIVE FINO
========================================================= */
@media (max-width: 520px){
  .container{ padding: 1.75rem 1rem 3rem; }
  .card{ padding: 1.2rem; }
  .drug-head{ align-items: flex-start; }
  .btn{ width: 100%; }
}

.seo-panel details {
  margin-top: 2rem;
  padding: 1rem 1.2rem;
  border-radius: 14px;
  background: rgba(255,255,255,0.03);
}

.seo-panel summary {
  cursor: pointer;
  font-weight: 600;
  font-size: 1rem;
}

.seo-panel h2,
.seo-panel h3 {
  margin-top: 1rem;
}