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Acid–Base and Electrolytes

Acid–base evaluation and biochemical corrections in critically ill patients.

🧪 Corrected Anion Gap


Δ/Δ (Delta–Delta)


🧂 Corrected Electrolytes

Corrected Sodium

Corrected Calcium

Table 2: Expected Compensation in Acid–Base Disorders

Metabolic Acidosis
For every ↓ [HCO₃⁻] of 1 mEq/L (from 25 mEq/L), pCO₂ should ↓ 0.85–1.2 mmHg (from 40 mmHg).
Metabolic Alkalosis
For every ↑ [HCO₃⁻] of 1 mEq/L (from 25 mEq/L), pCO₂ should ↑ 0.7 mmHg (from 40 mmHg).
Respiratory Acidosis
For every ↑ pCO₂ of 10 mmHg (from 40 mmHg), [HCO₃⁻]1 mEq/L if acute, or 3 mEq/L if chronic.
Respiratory Alkalosis
For every ↓ pCO₂ of 10 mmHg (from 40 mmHg), [HCO₃⁻]2–2.5 mEq/L if acute, or 5 mEq/L if chronic.